Because the blockchain works by verifying transaction history, and this verification process is labor-intensive and slow, only so many transactions can be verified in a certain timespan. So, if you sell your Bitcoin, but the purchase isn’t confirmed by the blockchain network, and the price of the currency changes, the sale won’t process. You'd have to sell your Bitcoin at whatever the new rate is (if you so choose to sell). Also due to the reality of blockchain, as well as for other reasons thus far unidentified, the Coinbase payout system can sometimes be unreliable. There have been reports of extensively delayed payout periods, and bugs sometimes keep the site from running as efficiently as it could or should. A word to the wise: if you are going to invest in and speculate on cryptocurrencies, do so carefully.
If you do have this much money tied up in Bitcoin, though, you may want a more secure space to store it. If this is the case, Coinbase offers a Coinbase vault, which has time-delayed withdrawals (giving you 48 hours to cancel a withdrawal) and the option of multiple approvers, increasing security by ensuring that all withdrawals are approved by multiple people. They also offer a multisig vault, which is basically an even more involved and more secure vault, requiring multiple keys to unlock.
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